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It’s no secret that per- and polyfluorinated alkyl substances (PFAS), also known as forever chemicals, are now well-established in the human body, with their presence detected in blood, umbilical cords and human milk. And while experts have linked PFAS exposure to health concerns like elevated cancer risks, endocrine disruption, developmental disruption and reduced immune system response, their impacts on the human brain remain relatively unknown.

However, a team led by researchers from the University at Buffalo has now identified 11 genes that could clear the way to better understanding how these chemicals affect brain tissue, and their level of neurotoxicity.

“Our findings indicate these genes may be markers to detect and monitor PFAS-induced neurotoxicity in the future,” G. Ekin Atilla-Gokcumen, lead co-corresponding author of the study and a chemistry professor at University at Buffalo, said in a statement.

The team exposed six types of PFAS to neuronal-like cells and lipids for a 24-hour period and found that these chemicals caused different expressions in 721 genes. These changes affected oxidative stress, protein synthesis, hypoxia signaling and amino acid metabolism, according to the study. They published their findings in the journal ACS Chemical Neuroscience.

Out of all the PFAS tested, perfluorooctanoic acid (PFOA) led to the widest spread changes in gene expression, affecting nearly 600 genes. By comparison, no other compound in the test affected expression of more than 147 genes. In July 2024, the U.S. Environmental Protection Agency (EPA) designated PFOA as a hazardous substance under the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA).

In total, 11 genes were impacted to express in the same way after exposure to all six compounds. Some of these differently expressed genes were important for neuronal cell survival, the study found.

“Each of these 11 genes exhibited consistent regulation across all PFAS that we tested. This uniform response suggests that they may serve as promising markers for assessing PFAS exposure, but further research is needed to know how these genes respond to other types of PFAS,” Atilla-Gokcumen explained.

The study results may help scientists further determine how these accumulative chemicals impact human brains, but as of right now, there are no known, safe and effective methods for removing PFAS from the human body. Even determining the level of exposure to PFAS is complicated, with testing costing up to $500, Verywell Health reported. While PFAS blood testing costs are required to be covered by insurance in New Hampshire, coverage varies or may be unavailable in other states.

G. Ekin Atilla-Gokcumen’s lab found 11 genes that are consistently affected by PFAS exposure, either expressing more or less, regardless of the type of PFAS. Meredith Forrest Kulwicki / University at Buffalo

In February 2024, a separate study found that the cholesterol medication cholestyramine was effective at reducing PFAS levels in plasma. However, the study included a small sample of subjects, and the researchers determined that the medication was not suitable for widespread, long-term use for the purpose of lowering PFAS levels because of the risk of side effects, Medical Xpress reported.

For now, medical experts will continue researching how PFAS affect human health alongside ways to reduce the accumulation of these compounds in our bodies, including through alternative materials that could provide the same benefits, such as water- and stain-resistance, with lower risks to human health.

“If we understand why some PFAS are more harmful than others, we can prioritize phasing out the worst offenders while seeking safer substitutes,” Atilla-Gokcumen explained. “For example, alternatives like short-chain PFAS are being explored, as they tend to persist less in the environment and accumulate less in biological systems. However, their reduced persistence may come at the cost of effectiveness in certain applications, and there are concerns about potential unknown health effects that require further investigation. Further research is needed to ensure these substitutes are genuinely safer and effective for specific applications. This research is a major step towards achieving this goal.”

In the meantime, the EPA has recommended reducing exposure by checking PFAS levels in your public water supply or private well, installing filters that reduce PFAS in water and avoiding consumption of fish from PFAS-contaminated waterways.

Further, the Environmental Working Group (EWG) recommended reducing exposure to forever chemicals by limiting consumption of food in takeout packaging or paper board packaging, skipping non-stick cookware in favor of materials like stainless steel and cast iron, and avoiding clothing with aftermarket waterproofing or stain-resistant treatments.

The post Scientists Identify 11 Genes That Could Help Understand How PFAS Affects the Brain appeared first on EcoWatch.

https://www.ecowatch.com/pfas-brain-health.html

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8 Ways to Reduce Your Impact Today

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With a full-time job, an active social life, and perhaps a kid or a pup to raise, it can be tough to fit in a commitment to the environment — especially if it seems to require added cost or responsibility.
Take heart, though, because there are many simple ways to reduce your impact on the planet that actually help you save money. Once you’re up to speed with the basics like changing your incandescent light bulbs to energy-efficient LEDs and shopping with reusable bags, check out these equally easy ways to simplify your go-go life.
Avoid take-out waste by bringing your own to-go containers. Image courtesy of dotpolka

This article contains affiliate links. If you make a purchase through these links we will receive a small commission from the sale that helps fund our work.

1. Say ‘No’ to To-Go Waste

Even if you’re constantly on the run, it’s possible to reduce the amount of waste you generate by packing your own reusable mug, water bottle, food containers, and cutlery. The majority of restaurant to-go containers are still made from plastics that don’t recycle easily, so they’re used once and then thrown away. Each plastic cup, fork, straw, and clamshell box costs money, and you can be sure this cost is passed onto consumers — not to mention the environmental costs of all that plastic waste.

2. Water Well

Water is a precious resource, which is often a fact overlooked in developed countries where we can just turn on the tap and get clean, safe water. However, according to a 2025 WHO/UNICEF report, 2.1 billion people globally still lack access to safely managed drinking water, and the global potable water supply is under pressure from climate change and population growth. You can decrease your water consumption by following a few simple steps.

Flush and run sparingly: The average toilet uses between 1.6 and 5.5 gallons of water per flush. If you are already “letting it mellow,” save even more water by turning on the tap only when absolutely necessary. There’s no need for the water to run when brushing your teeth, washing your hands, or doing the dishes, for example.

Make sure it’s really dirty before washing: Clothing, dishes, and your body should undergo the wash and rinse cycle only when necessary. Use the same water glass all day, and wear those jeans more than once.

3. Hang It Out to Dry

Clothes dryers are among the most energy-intensive household appliances. Most of us are not willing to give up cold milk and crisp veggies from the fridge, but we can easily use the dryer less often, which can add up to significant savings of energy and money.

As an added bonus, letting your clothes air dry extends their usable lives (it is much less taxing on the stitching and fabric), it gives you a good excuse to get outside in nice weather, and line-dried laundry smells better too! If you live in a place where drying clothes outside right now would mean wearing duds that are cold and wet, consider using indoor drying racks to accomplish the same energy-free job.

4. Lights, Camera, Out!

Many electronic devices — such as phone and camera chargers, televisions, and computers — continue to draw energy even when in the “off” position. To avoid phantom power use, unplug such devices or plug everything into a power strip you can turn off when not in use. Encourage these same practices at your workplace. And no matter where you are, always turn off unnecessary lights.

5. Be a Wise Post-Consumer

In the digital age, many of us still rely on a steady stream of paper in our offices, kitchens, and bathrooms. Here are some easy suggestions for keeping more trees outside.

Print sparingly: When you do need to hold a document in your hand, be sure it has been printed and/or copied on both sides, and of course, be sure to recycle when done.

Buy the highest level of post-consumer, recycled paper: From toilet paper to notebooks, there is rarely a reason to use virgin paper. Look for the percentage on the packaging (such as products made with 100% recycled or 50% post-consumer materials), and also look for paper that is processed chlorine-free (PCF).

Class it up with cloth: Reusable napkins are not just for fancy dinner parties. They can be washed and reused indefinitely. The same goes for old T-shirts or towels, which can be repurposed as rags and used instead of disposable paper towels.

6. Resist the Urge to Splurge

A lack of excess cash can serve as a great excuse to reduce your consumption. Here are a few suggestions to help you consume less.

Take a consumption vacation: Consider taking the day or week off from making any new purchases, with the exception of necessities such as health products and food. By doing this, you’re not only saving money, but you’re also reducing the waste created throughout the life cycle of each new product, the packaging used, and the fuel consumed and produced in transporting products from the original resources to the manufacturer to your local store.

Buy nice, don’t buy twice: For necessities, make sure that you buy the highest quality, most energy-efficient, environmentally friendly model available within your budget. From appliances (Energy Star) to food (Local Harvest), there are low-impact alternatives for almost everything on the market.

Public transportation
Do you have to drive, or can you take public transportation? Image courtesy of L.A. Urban Soul

7. Bid Your Car Adieu

We are a society that loves our cars, but there are many alternatives to a day spent solo in your gas-guzzling ride. Backing out of your car rut can also provide new opportunities to socialize and get some exercise.

Get on the bus: Many cities and towns have excellent public transportation systems that include buses, subways, and trains. You’ll be surprised at the new friends you make or the added reading time you find when not behind the wheel.

Carpool with friends or co-workers: Rideshare services now make it easier than ever to find a match. Uber’s UberX Share allows passengers traveling in the same direction to share a ride and reduce costs while cutting emissions. Lyft and Waze discontinued their shared rides programs in 2023.

Get on a bike or walk: While riding your bike or walking might take a little longer to reach your destination, the fresh air, reduced carbon emissions, and the exercise more than make up for the extra minutes.

Phone it in: Explore telecommuting or teleconferencing options with your employer to significantly reduce your daily commute. According to Global Workplace Analytics, a typical employer can save an average of $11,000 per half-time remote worker per year, while employees save between $2,000 and $6,500 annually from reduced commuting and related costs. Telecommuting just a few days a week will save you and your employer money.

8. Ban Planned Obsolescence

The more we view potential waste as building blocks for new products, the lower our overall impact will be. Granted, some products (“gum” comes to mind) are decidedly single-use items, but with a little creativity, many others can easily be creatively repurposed.

Originally published on April 6, 2009, article was most recently updated in January 2026.

The post 8 Ways to Reduce Your Impact Today appeared first on Earth911.

https://earth911.com/inspire/8-ways-to-reduce-your-impact-today/

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Green Living

Sustainability In Your Ear: Peter Fusaro’s Wall Street Green Summit Explores Financing The Renewables Transition

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Global investment in the energy transition reached $2.2 trillion in 2025, up 5% from the previous year despite political headwinds intensified. Peter Fusaro has watched this market evolve from a niche curiosity into a systemic financial concern. As founder of the Wall Street Green Summit, he’s spent a quarter century connecting capital to climate solutions. This year’s summit, the 25th in its history, will take place on March 10 and 11 in New York. This critical conversation arrives at an historic inflection point: insurance companies are withdrawing from climate-vulnerable states, AI data centers are straining electrical grids, and the economics of clean energy have fundamentally shifted.

Peter Fusaro, Founder of the Wall Street Green Summit, is our guest on Sustainability In Your Ear.

The energy transition’s bottleneck isn’t capital, it’s infrastructure. The U.S. went from 110 investor-owned utilities in 1992 to just 40 today, and consolidation meant underinvestment in transmission and distribution. Data centers consumed 2% of U.S. energy demand in 2020; Peter sees that climbing to 10-12% by 2030. Blackouts and brownouts are inevitable, he says. Yet his message is pragmatic optimism: ignore Washington and watch the capital markets and blue states where climate policy is embedded in law. Many companies are “green hushing,” quietly pursuing sustainability without public positioning. The energy industry thinks in 40-year cycles, making the current political moment a blip. “I’ve spent 56 years now in sustainability, before it had a name,” he says. “What I’ve learned is change takes decades.”

Peter argues that Wall Street has genuinely internalized climate as systemic risk—not because of ideology, but because of opportunity. “Wall Street likes exchanges, likes to trade, likes volatility, and certainly likes uncertainty,” he explains. “What people don’t understand about Wall Street, it’s about the edge. What’s the arbitrage opportunity?” The reinsurance industry has stepped forward aggressively, funding carbon credits and sustainability projects. Peter’s recent Earth911 article, “Climate Risk Has Become a Defining Economic Issue,” explores these themes in depth.

However, he sees natural gas and renewables dominating the next 15 years, while geothermal is enjoying a genuine renaissance. His optimism rests on a demographic bet: “I have a tremendous valuation on young people. I’m 75. They’re inheriting this world, and they get the sustainability message globally.” The summit attendees includes no government officials and no academics, just people in the trenches building and financing solutions.

You can learn more at TheWallStreetGreenSummit.com. Earth911 is a media sponsor for the event.

The post Sustainability In Your Ear: Peter Fusaro’s Wall Street Green Summit Explores Financing The Renewables Transition appeared first on Earth911.

https://earth911.com/podcast/sustainability-in-your-ear-peter-fusaros-wall-street-green-summit-explores-financing-the-renewables-transition/

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Green Living

Earth911 Inspiration: Nothing Is Perfect and Everything Is Perfect

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Sustainability is a series of experiments. No one is perfect and too many people don’t try to help the Earth because they think they won’t make a difference. Author Alice Waters reminds us that every tree is beautiful and we can be, too, if we forget perfection and focus on living well: “In nature, nothing is perfect and everything is still perfect. Trees can be contorted, bent in weird ways, and they’re still beautiful.”

Earth911 inspirations. Post them, share your desire to help people think of the planet first, every day. Click the poster to get a larger image.

"In nature, nothing is perfect and everything is perfect ..." --Alice Walker

This poster was originally published on November 29, 2019.

The post Earth911 Inspiration: Nothing Is Perfect and Everything Is Perfect appeared first on Earth911.

https://earth911.com/living-well-being/earth911-inspiration-nothing-is-perfect-and-everything-is-perfect/

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