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A major fund for biodiversity remains starved of resources more than five months after its launch – with no money yet put forward by the large companies who could contribute.

The “landmark” Cali Fund – which could generate billions of pounds each year – was created under the UN Convention on Biological Diversity (CBD) at the COP16 nature negotiations in Cali, Colombia last autumn.

Countries agreed that certain companies “should” pay into the fund, but this is not legally binding and donations are, ultimately, voluntary.

The fund is designed to be a way for companies who rely on nature’s genetic resources to share some of their earnings with the developing, biodiverse countries where many of the original resources are found.

Companies use genetic data from these materials to develop products, such as vaccines and skin cream.

Emails released to Carbon Brief under the UK Freedom of Information (FOI) Act show that companies were contacted with opportunities to be involved in the Cali Fund before its launch in February 2025.

Pharmaceutical giant AstraZeneca did not take up an offer from a UK government department to be a “frontrunner” in committing to donate to the fund, the emails show.

GSK, another major company in the sector, also did not confirm its position.

These are the UK’s two largest pharmaceutical companies and they could each potentially contribute tens of millions of pounds to the fund, based on current guidelines.

Earlier this year, a spokesperson for the CBD said that the first contributions to the Cali Fund could be announced in spring.

One US biotechnology company has pledged to contribute to the fund in the future, but, for now, the fund remains empty.

Company hesitancy could be “driven by industry bodies” who “don’t want unhappy precedents to be set” on the level of funding, a researcher who was involved in the fund negotiations tells Carbon Brief.

Lack of funds

Companies all around the world use genetic materials from plants, animals, bacteria and fungi to develop their products.

There are existing rules in place to secure consent and compensation, if companies or researchers physically travel to a country to gather these materials.

But, currently, much of this information is available in online databases – with few rules in place around the requirements needed for access. This genetic data is known as digital sequence information (DSI).

Launch of the Cali Fund at the resumed COP16 negotiations in Rome, Italy in February 2025. Credit: IISD/ENB | Mike Muzurakis
Launch of the Cali Fund at the resumed COP16 negotiations in Rome, Italy in February 2025. Credit: IISD/ENB | Mike Muzurakis

In an effort to close the loophole, almost every country in the world agreed in 2024 to set up the Cali Fund.

The agreement outlines that large companies in sectors including pharmaceutical, cosmetic, biotechnology, agribusiness and technology “should” contribute to the fund to share back a cut of the money they earn from the use of these materials. (See: Carbon Brief’s infographic on DSI.)

However, these contributions are voluntary. Many African and Latin American countries sought a legally binding mechanism around this issue at COP16, but this did not happen.

The fund officially opened at the resumed COP16 negotiations in Rome in February 2025.

With the fund still empty more than five months later, a spokesperson for the CBD secretariat tells Carbon Brief that a US-based biotechnology firm, Ginkgo Bioworks, is the first to “indicat[e] its intention to contribute”.

The CBD, also acting as the interim secretariat for the new fund, “continue[s] to engage with business associations to raise awareness and secure funding”, the spokesperson says.

They add that a decision-making body and a steering committee have been set up.

The contribution page on the Cali Fund website saying: "The work of the The Cali Fund is possible thanks to the efforts of 0 contributors. Since together they have contributed 0.
The contribution page on the Cali Fund website, at the time of publication. Source: Multi-partner Trust Fund Office

The CBD received “positive feedback and engagement” from companies about the fund, the UN biodiversity chief Astrid Schomaker said in a February press conference. She added that donations were expected “very soon”, but not in “massive numbers”.

Carbon Brief contacted Ginkgo Bioworks for comment, but did not receive a response in time for publication.

‘Frontrunner’ contributors

Through an FOI request, Carbon Brief received email correspondence between the UK Department for Environment, Food & Rural Affairs (Defra), major pharmaceutical companies AstraZeneca and GSK, and trade group the Association of the British Pharmaceutical Industry (ABPI) between August 2024 and April 2025. (Carbon Brief has uploaded the FOI documents it received to a Google Drive folder.)

A representative from Defra told AstraZeneca in December 2024 that they were contacting a “select number of companies that will likely be frontrunners with the Cali Fund and make contributions – leading the way for others to follow suit”.

The Defra employee said that they had received “some positive signals from these companies” and asked if AstraZeneca was interested in “demonstrating commitment in this start-up phase of the fund”. This email said:

“I hope this finds you well – and thanks for joining various calls over the last few weeks on DSI, it’s great to have you involved. I know that AZ have been really forward leaning on ABS issues in the past (including under your leadership) and now that we have the Cali Fund for benefit sharing from the use of DSI, I wondered if we might pick up the conversation on any role AZ might be able to take as an early mover in the ABS world?

“We are beginning to have conversations with a select number of companies that will likely be frontrunners with the Cali Fund, and make contributions – leading the way for others to follow suit – and we have had some positive signals. Do you think there might be any interest from AZ in demonstrating commitment in this start-up phase of the Fund? If it would be helpful to have a conversation to chat through, please do let me know and I’d be super happy to set something up.” 

The AstraZeneca representative responded to say the company was “in the process of conducting an assessment to define our position” on the fund and that they would “welcome a conversation” when this concluded.

A Defra official contacted the company again in early January to say the government was preparing meetings between a member of the CBD secretariat and several businesses “that have shown some interest in leading others by making the first contributions to the fund”.

They asked if AstraZeneca was interested in attending this meeting. The company declined, but said it would be interested in future discussions.

An AstraZeneca spokesperson declined to respond to Carbon Brief’s questions, but Carbon Brief understands that the company is still reviewing its position on the fund.

Animals in extinction display at the green zone of COP16 biodiversity negotiations in Cali, Colombia on 19 October 2024.
Animals in extinction display at the green zone of COP16 biodiversity negotiations in Cali, Colombia on 19 October 2024. Credit: Associated Press / Alamy Stock Photo

Similar exchanges took place between representatives from Defra and GSK ahead of the Cali Fund launch.

GSK was invited to the same January meetings, but the company said nobody was available to attend. A Defra official contacted GSK in February to update on progress with the fund, outlining that it would be launched in Rome, “accompanied by a platform for announcements and press coverage”.

The Defra official asked GSK to let them know “if you think there might be any opportunities for GSK – we would obviously love to add your voice to the positive coverage”. The email read:

“As a broader update, we are still expecting the Fund to formally launch in Rome at COP16.2, and that will be accompanied by a platform for announcements and press coverage. We are also working with another CBD Party to explore the option of putting on some kind of reception for those businesses that are leading the way together.

“Please do let me know if you think there might be any opportunities for GSK – we would obviously love to add your voice to the positive coverage!”

They also asked if GSK would like to see a draft version of a press release from the CBD about the launch of the Cali Fund, along with other businesses “that are interested in being part of the launch”.

(The Cali Fund launch press release did not contain any quotes or donation announcements from companies.)

GSK said that it was “awaiting further clarification on a number of key elements” before making a decision on the Cali Fund and would respond “in due course”.

The company “support[s] the intent” behind the fund, a spokesperson tells Carbon Brief, adding:

“We’ll make a decision regarding voluntary contributions when more information becomes available about how the Cali Fund sits alongside other multilateral mechanisms. 

“GSK was one of the first companies to publish a nature strategy and we continue to work on delivering our plan to address our nature impacts and invest in nature protection and restoration.”

A Defra spokesperson tells Carbon Brief:

“Nature underpins everything and those who profit from the use of genetic data should pay nature back. The Cali Fund provides the route for companies to do that.

“The government is committed to continuing to engage constructively with industry to drive contributions and champion the fund to protect nature and sustain innovation.”

The UK and Chile recently launched the “friends of the Cali Fund” group, which “brings together” governments and businesses to “champion” benefits sharing, a UK government statement said. Norway, Germany, the Netherlands and Colombia have also joined this group.

UK companies could contribute £64m

Contributions to the Cali Fund are voluntary. They will depend on whether companies that rely on the use of genetic data will then admit to using genetic materials and decide to pay into the fund.

The agreement behind the fund, which is not legally binding, outlined that companies “should” contribute 1% of their profits, or 0.1% of their revenue. These are an “indicative rate”.

Words that are more binding, such as “will” and “shall”, were included in non-paper negotiation texts during the talks. But the final agreement referred to a fund that companies “should” pay into, which was criticised by some experts at the time.

At least half of the money raised will go towards meeting the “self-identified” needs of Indigenous communities in developing countries, particularly women and young people.

The overall fund could generate between $1bn and $10bn each year, according to a 2024 analysis requested by the CBD.

People celebrate after the establishment of a subsidiary body for Indigenous peoples at the COP16 negotiations in Cali, Colombia on 2 November 2024. Credit: IISD/ENB | Mike Muzurakis
People celebrate after the establishment of a subsidiary body for Indigenous peoples at the COP16 negotiations in Cali, Colombia on 2 November 2024. Credit: IISD/ENB | Mike Muzurakis

The cache of information released under FOI to Carbon Brief also includes a report on the impacts of a mandatory payment for using digital sequence information, which was prepared for Defra by consultancy company ICF in July 2024.

It estimated that a mandatory 1% levy on the profits of large UK companies “who are considered DSI-dependent” could generate nearly £64m ($85m) for the fund.

The report compared three different benefit-sharing mechanisms around genetic data: a mandatory levy on UK profits/revenues; a flat fee; or a subscription fee.

All options would negatively impact on “innovation” to varying degrees, the report said, but a mandatory levy on profits was found to have the “least negative impact on competition and innovation”.

Table from Defra titled "Scenario 1a: Levy on DSI dependent company profits"
Analysis from a report on digital sequence information, prepared for Defra by ICF.

During the Cali Fund negotiations last October, the Guardian reported that AstraZeneca “said it may cut jobs” in the UK, if such a levy was introduced. An AstraZeneca spokesperson denied the comments, the newspaper said.

Based on the “indicative” contribution rates of 1% of profits or 0.1% of revenue, Carbon Brief estimates that AstraZeneca could potentially contribute as much as £41-66m ($54-88m) and GSK £31-35m ($41-46m) each year to the fund.

AstraZeneca reported revenue of £41bn ($54bn) and £6.6bn ($8.7bn) in profit before tax in 2024. GSK’s revenue that year was around £31bn ($40bn) and its pre-tax profit was £3.5bn ($4.6bn).

Lobbying concerns

At COP16, many observers were concerned about industry lobbying around digital sequence information.

DeSmog analysis of COP16 attendees highlighted the presence of big pharmaceutical companies, powerful industry groups and agribusiness at the talks.

The International Federation of Pharmaceutical Manufacturers and Associations (IFPMA), a global pharmaceutical trade group, said it had “serious concerns” about proposals around the fund at the start of COP16. The group said it would result in “regulatory and financial barriers that would stifle innovation, delay R&D [research and development] and complicate compliance”.

The emails obtained by Carbon Brief show that, in August 2024, a GSK representative told Defra that the company believed proposals for a “simplistic payment mechanism based on revenues would be disproportionate and could hinder the development of new medicines and vaccines”. This email said:

“You were asking for views on the call, so I also wanted to take the opportunity to share GSK’s perspective at this time. We are supportive of a practical and fair multilateral mechanism for benefit-sharing from the use of digital sequence information on genetic resources. The criteria for this mechanism listed in decision 15/9 are particularly important, specifically the fact that it must not hinder research and innovation.

“We are concerned that the current proposals for a simplistic payment mechanism based on revenues would be disproportionate and could hinder the development of new medicines and vaccines. We would support the consideration of other models, for example a subscription model whereby organisations that access open source DSI databases make a contribution to the global fund.

“This would have the benefit of broadening the base of contributors. Tiers could be established based on size of organisation, so that the contributions were proportionate and fair.”

The FOI release also shows that ABPI chief executive, Dr Richard Torbett, wrote a letter to UK nature minister Mary Creagh on 17 October 2024, a few days before the COP16 summit began.

He “urge[d]” the government to not agree on the details of a fund “until more work has been conducted to understand the implications of proposals”.

Torbett said that, if this was not possible, the ABPI wanted the government to support an option put forward by Japan and South Korea to introduce a voluntary funding mechanism.

Hesitancy potentially ‘driven by industry bodies’

In a statement after COP16, the IFPMA’s director general, Dr David Reddy, said the decision creating the Cali Fund “does not get the balance right between the intended benefits of such a mechanism and the significant costs to society and science that it has the potential to create”.

The FOI release obtained by Carbon Brief includes a 20 March 2025 document from the ABPI discussing possible future changes to the fund.

The group said the fund “contains and omits several features which make it unlikely to attract significant contributors”. The ABPI “cannot over-emphasise the importance” of the fund being voluntary, the document said, with companies “free to decide” if and how much they want to contribute.

The ABPI urged the UK to discourage any country-level implementation of the COP16 digital sequence information agreement, arguing that “conflicting” action on a national, rather than global, level would “reduce the (already weak) incentives to contribute to the Cali Fund”.

The ABPI also criticised the agreed 0.1% and 1% contribution rates for companies, saying they are “regarded by industries generally as being unrealistic and likely to impact innovation”.

The opening plenary of the resumed COP16 negotiations at the headquarters of the UN Food and Agriculture Organization in Rome on 25 February 2025. Credit: IISD/ENB | Mike Muzurakis
The opening plenary of the resumed COP16 negotiations at the headquarters of the UN Food and Agriculture Organization in Rome on 25 February 2025. Credit: IISD/ENB | Mike Muzurakis

The ABPI declined to respond to Carbon Brief’s questions and referred Carbon Brief to the global trade group, the IFPMA. A spokesperson for the IFPMA also declined to respond to questions and pointed towards the company’s public statements on the issue.

Dr Siva Thambisetty, an associate professor of law at the London School of Economics and Political Science and project lead on an ocean biodiversity research group, believes the first contribution to the fund is a “prize that’s just waiting to be won”. She tells Carbon Brief:

“It would be an absolute coup for a responsible DSI company to be the first to make a contribution to the Cali Fund. Investors should be very interested in that company, for instance.

“We’ve got to move to a biodiversity market where investors are asking whether companies they invest in are contributing to remedy and repair at a global level through appropriate monetary benefit sharing.”

Thambisetty believes that this is “low-hanging fruit”, but acknowledges that companies have varying opinions on the fund and that the “majority might be unsure how to deal with this”. She adds:

“I think the hesitancy is mostly being driven by industry bodies because they don’t want unhappy precedents to be set. There is a collective action problem and the first company to break cover will be sending a signal that will be received differently by different people.”

The post Revealed: ‘Cali Fund’ for nature still empty as emails show industry hesitation appeared first on Carbon Brief.

Revealed: ‘Cali Fund’ for nature still empty as emails show industry hesitation

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Greenhouse Gases

Heatwaves driving recent ‘surge’ in compound drought and heat extremes

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Drought and heatwaves occurring together – known as “compound” events – have “surged” across the world since the early 2000s, a new study shows. 

Compound drought and heat events (CDHEs) can have devastating effects, creating the ideal conditions for intense wildfires, such as Australia’s “Black Summer” of 2019-20 where bushfires burned 24m hectares and killed 33 people.

The research, published in Science Advances, finds that the increase in CDHEs is predominantly being driven by events that start with a heatwave.

The global area affected by such “heatwave-led” compound events has more than doubled between 1980-2001 and 2002-23, the study says.

The rapid increase in these events over the last 23 years cannot be explained solely by global warming, the authors note.

Since the late 1990s, feedbacks between the land and the atmosphere have become stronger, making heatwaves more likely to trigger drought conditions, they explain.

One of the study authors tells Carbon Brief that societies must pay greater attention to compound events, which can “cause severe impacts on ecosystems, agriculture and society”.

Compound events

CDHEs are extreme weather events where drought and heatwave conditions occur simultaneously – or shortly after each other – in the same region.

These events are often triggered by large-scale weather patterns, such as “blocking” highs, which can produce “prolonged” hot and dry conditions, according to the study.

Prof Sang-Wook Yeh is one of the study authors and a professor at the Ewha Womans University in South Korea. He tells Carbon Brief:

“When heatwaves and droughts occur together, the two hazards reinforce each other through land-atmosphere interactions. This amplifies surface heating and soil moisture deficits, making compound events more intense and damaging than single hazards.”

CDHEs can begin with either a heatwave or a drought.

The sequence of these extremes is important, the study says, as they have different drivers and impacts.

For example, in a CDHE where the heatwave was the precursor, increased direct sunshine causes more moisture loss from soils and plants, leading to a drought.

Conversely, in an event where the drought was the precursor, the lack of soil moisture means that less of the sun’s energy goes into evaporation and more goes into warming the Earth’s surface. This produces favourable conditions for heatwaves.

The study shows that the majority of CDHEs globally start out as a drought.

In recent years, there has been increasing focus on these events due to the devastating impact they have on agriculture, ecosystems and public health.

In Russia in the summer of 2010, a compound drought-heatwave event – and the associated wildfires – caused the death of nearly 55,000 people, the study notes.

Saint Basil's Cathedral, on Red Square, in Moscow, was affected by smog during the fires in Russia in the summer of 2010.
Saint Basil’s Cathedral, on Red Square, in Moscow, was affected by smog during the fires in Russia in the summer of 2010. Credit: ZUMA Press, Inc. / Alamy Stock Photo

The record-breaking Pacific north-west “heat dome” in 2021 triggered extreme drought conditions that caused “significant declines” in wheat yields, as well as in barley, canola and fruit production in British Columbia and Alberta, Canada, says the study.

Increasing events

To assess how CDHEs are changing, the researchers use daily reanalysis data to identify droughts and heatwaves events. (Reanalysis data combines past observations with climate models to create a historical climate record.) Then, using an algorithm, they analyse how these events overlap in both time and space.

The study covers the period from 1980 to 2023 and the world’s land surface, excluding polar regions where CDHEs are rare.

The research finds that the area of land affected by CDHEs has “increased substantially” since the early 2000s.

Heatwave-led events have been the main contributor to this increase, the study says, with their spatial extent rising 110% between 1980-2001 and 2002-23, compared to a 59% increase for drought-led events.

The map below shows the global distribution of CDHEs over 1980-2023. The charts show the percentage of the land surface affected by a heatwave-led CDHE (red) or a drought-led CDHE (yellow) in a given year (left) and relative increase in each CDHE type (right).

The study finds that CDHEs have occurred most frequently in northern South America, the southern US, eastern Europe, central Africa and south Asia.

Charts showing spatial and temporal occurrences over study period
Spatial and temporal occurrence of compound drought and heatwave events over the study period from 1980 to 2023. The map (top) shows CDHEs around the world, with darker colours indicating higher frequency of occurrence. The chart in the bottom left shows how much land surface was affected by a compound event in a given year, where red accounts for heatwave-led events, and yellow, drought-led events. The chart in the bottom right shows the relative increase of each CDHE type in 2002-23 compared with 1980-2001. Source: Kim et al. (2026)

Threshold passed

The authors explain that the increase in heatwave-led CDHEs is related to rising global temperatures, but that this does not tell the whole story.

In the earlier 22-year period of 1980-2001, the study finds that the spatial extent of heatwave-led CDHEs rises by 1.6% per 1C of global temperature rise. For the more-recent period of 2022-23, this increases “nearly eightfold” to 13.1%.

The change suggests that the rapid increase in the heatwave-led CDHEs occurred after the global average temperature “surpasse[d] a certain temperature threshold”, the paper says.

This threshold is an absolute global average temperature of 14.3C, the authors estimate (based on an 11-year average), which the world passed around the year 2000.

Investigating the recent surge in heatwave-leading CDHEs further, the researchers find a “regime shift” in land-atmosphere dynamics “toward a persistently intensified state after the late 1990s”.

In other words, the way that drier soils drive higher surface temperatures, and vice versa, is becoming stronger, resulting in more heatwave-led compound events.

Daily data

The research has some advantages over other previous studies, Yeh says. For instance, the new work uses daily estimations of CDHEs, compared to monthly data used in past research. This is “important for capturing the detailed occurrence” of these events, says Yeh.

He adds that another advantage of their study is that it distinguishes the sequence of droughts and heatwaves, which allows them to “better understand the differences” in the characteristics of CDHEs.

Dr Meryem Tanarhte is a climate scientist at the University Hassan II in Morocco, and Dr Ruth Cerezo Mota is a climatologist and a researcher at the National Autonomous University of Mexico. Both scientists, who were not involved in the study, agree that the daily estimations give a clearer picture of how CDHEs are changing.

Cerezo-Mota adds that another major contribution of the study is its global focus. She tells Carbon Brief that in some regions, such as Mexico and Africa, there is a lack of studies on CDHEs:

“Not because the events do not occur, but perhaps because [these regions] do not have all the data or the expertise to do so.”

However, she notes that the reanalysis data used by the study does have limitations with how it represents rainfall in some parts of the world.

Compound impacts

The study notes that if CDHEs continue to intensify – particularly events where heatwaves are the precursors – they could drive declining crop productivity, increased wildfire frequency and severe public health crises.

These impacts could be “much more rapid and severe as global warming continues”, Yeh tells Carbon Brief.

Tanarhte notes that these events can be forecasted up to 10 days ahead in many regions. Furthermore, she says, the strongest impacts can be prevented “through preparedness and adaptation”, including through “water management for agriculture, heatwave mitigation measures and wildfire mitigation”.

The study recommends reassessing current risk management strategies for these compound events. It also suggests incorporating the sequences of drought and heatwaves into compound event analysis frameworks “to enhance climate risk management”.

Cerezo-Mota says that it is clear that the world needs to be prepared for the increased occurrence of these events. She tells Carbon Brief:

“These [risk assessments and strategies] need to be carried out at the local level to understand the complexities of each region.”